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Array Comparative Genomic Hybridization

Genetics Center is pleased to offer the latest in array-based comparative genomic hybridization (CGH) testing. Our high-resolution array containing 180,000 oligonucleotide and SNP probes is based on the International Standards for Cytogenomic Arrays (ISCA) Consortium chip design. As there are many abnormal phenotypes that are associated with chromosomal imbalances (subtle gains or losses of genetic material), the identification of specific abnormalities (or copy number variants) is helpful for accurate diagnosis and medical management. Array CGH is a technology with the ability to detect chromosome imbalances beyond that of more conventional techniques...read more.

Genetics Center is pleased to offer the latest in array-based comparative genomic hybridization (CGH). testing in a prenatal setting. Array CGH is a technology with the ability to detect chromosome imbalances beyond that of more conventional techniques. Our high-resolution targeted prenatal array (GCPrenatal Array) containing a combination of 60,000 oligonucleotide and SNP probes, is designed to cover 312 specific regions known to be associated with childhood-onset disorders. This includes detection of loss of heterozygosity for six clinically relevant chromosomes, including chromosomes 7, 11, 14, 15, 16 and 20,which may indicate uniparental disomy (UPD). As there are many abnormal phenotypes...read more.